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Secale Cornutum - General symptoms

Claviceps Purpurea, Ergot, Secale, Secal, Secale cereale Sec.

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HPUS indication of Secale Cornutum: Restlessness

Below are the main rubriks (i.e strongest indications or symptoms) of Secale Cornutum in traditional homeopathic usage, not approved by the FDA.

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Ergota (Ergot or Argot, Fr., a cock's spur); Ergot of rye; Spurred rye; Secale clavatum; Mater secalis; Seigle ergot, (Fr.); Mutterkorn; Kornmutter (G)p

The true nature of Ergot, whether a product of diseased vegetable life or a true vegetable itself, has long been a source of a great diversity of opinion. But according to the latest authorities, Secale cornutum belongs to the order Thallophyta cellular or non-vascular plants. This is the lowest order of the vegetable kingdom and is divided into two classes. Algae and Fungi, which is based upon the presence in the former of Chlorophyll, and its absence in the latter. They produce no differentiation of root, stem or leaf. In the lowest members of the group there is no sexual reproduction.

in the higher the sexual union may be a single spore, or a mass of spores, or a fructification within which spores are found. De Candolle and Fries in 1816, and Léveille, in 1827, added by their researches, much to our knowledge of the intimate structure of Secale, but it remained to L. R. Tulsane, in 1853, by his admirable monograph "Mémoire sur l'Ergot des Glumacées", to clear up many disputed points in the formation, growth and development of this fungus, and this monograph is still referred to by nearly every author as the best work on the subject. Yet Fluckiger and Hanbury maintain that the true nature of Ergot has not been settled even by Tulsane's long continued and admirable researchesp .

Neither in external form, nor in anatomical structure, does Ergot exhibit any resemblance to a seed, although its development takes place between the flowering time and that at which the rye begins to ripen. It has been regarded as a complete fungus, and as such was named by De Candolle Sclerotium Claves, and by Fries Spermoëdia Clavius. Not further change occurs in the Ergot while it remains in the ear.

but laid on damp earth, interesting phenomena take place..

To the use of rye flour, more or less adulterated with Ergot, is attributed the formidable disease known in modern medicine as Ergotism, but in early times by a number of names Morbus spasmodicus, Convulsivus Malignus, Epidemicus vel Cerealis, Convulsion Raphania, Ignus Sancti Antonia. There is now little doubt that the terrible epidemics which occurred in France in the tenth century and in Spain in the twelfth century were due to Ergot. Fluckiger and Hanbury says "In the year 1596 Hessia and the adjoining regions were ravaged by a frightful pestilence, which the medical faculty of Marburg attributed to the presence of Ergot in the cereals consumed by the population. The same disease appeared in France in 1630.

in Voightland, Saxony, in the years 1648, 1649 and 1675.

again in various parts of France in 1650, 1670 and 1674. Freiburg and vicinity were visited by the same malady in 1702.

other parts of Switzerland in 1715-16.

Saxony and Lusatia in 1716.

many other districts of Germany in 1717, 1722, 1736 and 1741-42. The last European epidemic occurred after the rainy season of 1816 in Lorraine and Burgundy, and proved very fatal among the poorer classes.".

"In 1883-84, during the building of the West Shore Railroad, I was called upon to treat many of the Italian employés for an eruption which appeared upon the body in many places, but usually on the shoulders, neck and inner surface of the upper arms. In the majority of cases it was on the right side alone, but if on both sides was always worse on the right. The eruption would begin in a small point, life the prick of a pin, which would soon assume a pimple-like form and finally become pustular and as large as a small pea. At other times they would appear as large as a small boil (half an inch across the base), of a dark bluish hue, shading off to the healthy color of the skin an inch or more from centre of boil. They were intensely painful to touch, aching, burning and itching, better from light rubbing, worse from scratching, worse from heat. The small one would dry up leaving no cicatrix, but the large ones would fill slowly with a bright yellow pus-like material, or at times a bloody, watery serum, remaining open for days, having extremely painful edges and base, and discharging towards its close a thick, dirty, offensive serum. They were decidedly indolent in character, and left a prominent cicatrix. Cool air blowing over the eruption would relieve the itching and burning, but not the pain. Secale, Lachesis Lachesis, Causticum Causticum were the remedies chiefly indicated. Having learned that the Italians are largely of rye bread made of a very poor and cheap quality of flour, while other nationalities (not eating the rye bread) did not suffer from it at all, I attributed the eruption to poisoning by Ergot in the bread.

and if a patient presented without an interpreter I usually gave Secale, which would cure about seven cases in ten.".

"H. G. K. A miller of Pittsford, N. Y., informs me that he is unable to grind rye even for a short time. Upon entering a rye mill, had a sensation of constriction in the throat, great difficulty in breathing.

difficult inspiration.

expiration accompanied by soreness all over the chest.

oppression of the chest.

soreness of the chest.

intercostal pains. pricking of the tongue.

"The foregoing symptoms are distinctively of rye grinding.

when grinding wheat no symptoms follow. He also informs me that in two rye mills in Rochester he knows a number of individuals engaged therein who suffer as above with the addition of an eruption particularly on the neck, chest, behind the ears and around the waist. The eruption is pustular, itching violently, and discharges a yellow matter. One man he knew who was compelled to give up rye grinding because of the many boils and carbuncles. He recovered entirely after changing his occupation. Nearly all rye grinders have enlarged finger joints and poor teeth." .

March 18th. - The eruption appeared on the left shoulder, several small pustules in a cluster, with the same characteristic soreness. Ceased taking drug. Dull, heavy headache in forehead and eyes.

much throbbing. Before the menses (four or five days) a dark colored leucorrhea was observed, not very profuse, but attended with a tired and uneasy feeling in the pelvis.

Was attacked while at lectures with palpitation which continued nearly all the afternoon. Could feel the heart flutter and remit. Pulse 108 and 110. Violent throbbing of the carotids, faint for several hours. Never had palpitation before in her life. Headache.

full, throbbing, bursting, like a Glonoin Glonoine headache (has proved Glonoin Glonoine), only not so sore on shaking the headp.

Attacks of severe pressure and constriction in region of stomach extending through to spine, extremely painful and followed in half an hour by vomiting of tasteless fluid or of contents of stomach, thereupon an intermission of several hours occurred.

during attack region of stomach felt as if contracted, and on percussion gave a tympanitic note.

has three to four attacks dailyfont.

Hematemesis. attacks preceded by pains in epigastrium and nausea, pain going to left side when pressure is made in epigastrium.

marked protrusion in left hypochondrium, with pain.

blood red, never containing particles of food, and when collected in basin appears more like bloody serum than pure blood and is of offensive odor, quantity vomited not very large.

frequent chilliness at night, followed by profuse sweat.

strength not much impaired.

appetite and sleep goodfont.

Palpitation. hot forehead.

inclination to sleep. spasmodic shocks from right half of chest into right arm and leg.

in paroxysms every two or three hours.

oftener in night, after each meal.

less in open air. coldness and numbness of right hand, with tingling in fourth and fifth fingers.

loss of muscular power and feeling in hand.

after sexual excess.

Hard, hoarse cough, with but little expectoration.

pains nearly all over front part of chest, worse from coughing and motion.

for several years tenderness of lower cervical and upper dorsal spinous processes, with stiffness of neck.

worse from every exertion or strain upon spine.

pressure upon diseased portion of spine produces pain there, as well as through chest, with irritation to coughfont.

Stitches in upper dorsal vertebrae (between shoulders), constant when sitting, intermittent when standing, at times extending into hands, worse by pressure upon vertebrae.

frequent formication through all limbs.

at times rigidity and spasmodic stretching of fingers so that for several minutes he cannot sew.

frequent pressure and swelling beneath epigastrium.

pain in back worse when sewingfont.

Difficult, staggering gait.

complete inability to walk, not for want of power but on account of a peculiar unfitness to perform light movements with limbs and hands.

contraction of lower limbs on account of which patient staggers.

trembling of limbs, sometimes attended with pains.

formication of hands and feet.

excessive sensation of heat, with aversion to heat or being covered.

Diarrhea very exhausting, pernicious.

very offensive. involuntary, profuse, watery, putrid, brown.

discharged with great force.

very exhausting. urine suppressed.

painful with great prostration.

painless with tingling and numbness in limbs.

putrid, fetid, colliquative, patient does not want to be covered or to be near the heat, but prefers to be in the air or wishes to be fanned.

sudden attacks. of children, discharges whitish, watery.

chronic in overfed children, great prostration.

during August. great stools undigested, or watery, at times yellowish, also greenish, with forcible expulsion, accompanied by discharge of flatus.

paralytic weakness of sphincter ani with involuntary dischargesfont.

Stools yellowish. greenish, brownish.

watery and flocculent.

colorless, watery. profuse.

frequent. putrid. gushing.

involuntary. watery, slimy thin, olive green.

offensive, watery. fetid, dark colored.

thin, involuntary. watery, yellowish or greenish, discharged rapidly with great force and even involuntarily.

painless, without effort and with great weakness.

Five to ten minutes after taking least quantity of food, severe colic which made her bend double and cry out.

pain begins between region of stomach and navel, extends thence to sides and rest of abdomen and down to sacral region, accompanied by severe urging and tenesmus, followed by a thin, slimy, yellowish stool with some relief of pain.

four to five such attacks follow each other.

then relief until she eats again.

four to five evacuations during night.

she compares pains to labour pains.

great thirst. thick mucous coating on tongue.

sleep disturbed. prostration. Diarrheafont.

Uncomfortable fullness of abdomen, with transient pinching pains in upper abdomen as from flatus.

at night severe cutting pains throughout whole abdomen.

restless anxious tossing about, with short and unrefreshing naps.

during night anus firmly closed, "as if locked up;" in morning frequent short watery evacuations, in gushes, preceded by cutting pains in abdomen.

Patient cold, almost pulseless, with spasmodic twitching of muscles in various parts of body.

spreads fingers asunder.

eyes sunken, features pinched.

much spasmodic retching although not much vomiting.

skin harsh, shriveled, dry, as if there were no moisture left in system.

urine suppressed. tingling or formication all over body.

stools profuse, watery, ejected with great violence.

is cold but cannot bear to be coveredfont.

Putrescence of uterus.

abdomen distended, not very painful.

discharge from vagina, brownish, offensive.

ulcers on external genitals discolored and rapidly spreading.

burning hot fever, interrupted by shaking chills.

small, sometimes intermittent pulse.

great anguish, pain in pit of stomach, vomiting decomposed matter.

offensive diarrhea. suppressed secretion of urine.

skin covered with petechial and miliary eruptions or shows discolored, inflamed places, with a tendency to mortification.

the patient lies either in quiet delirium or grows wild with great anxiety and a constant desire to get out of bed. Metritisfont.

The uterus that had previously been in a normal condition descended so that it almost protruded, was hot and painful.

os open as large as middle finger.

excessive desire to urinate.

labor pains only relieved by wet bandages or pressure upon abdomen.

lasted three days, did not miscarry though os remained open during this period.

afterward uterus gradually ascended, pains diminished, and after five or six days os contracted.

went on to eighth month, when she miscarried.

Uterine hemorrhage when uterus is engorged.

with pains in sacrum, extending down thighs and pressing into lower abdomen of a pregnant woman.

profuse protracted flow.

tearing, cutting colic, cold extremities and cold sweat, weak, hemorrhage worse from slightest motion, blood thin and black, black lumpy or brown fluid, of disgusting smell.

black liquid bloodfont.

A woman, aet. 45, passed through a normal confinement seven years ago.

miscarried about two years ago, hemorrhage kept up for five months under allopathic treatment, with exacerbation during time of menstruation.

after ceasing for seven months, hemorrhage set in again with slight intermission of one or two weeks.

excessive anemia. sunken features.

skin cold and dry. pulse small and quick.

heavily coated tongue.

loss of appetite. headache.

since five days, daily ten or twelve painless stools, of mucous, watery, sometimes foul smelling masses.

thin, black, foul-smelling bloody dischargesfont.

Feeble and extremely emaciated, skin flaccid, face very pale and sunken, with an expression of suffering, mucous membranes pale and cool, hands and feet deficient of natural warmth, action of heart quickened, breathing short and oppressed, pulse very small, 120.

abdomen distended. os uteri very open, with indented and puffy edges, flaccid and soft, vagina tender and cool.

manual examination caused much uneasiness and flooding.

violent headache limited to one spot, throbbing in temples, roaring in ears, giddiness on slightest movement.

enfeebled nervous system showed extraordinary excitability.

many times in day, and especially at night, cramps in calves and spasmodic twitching of limbs, causing exhaustion, remains several hours in bed as if paralysed.

digestion and sleep disturbed to some extent.

hemorrhage still continued.

even in horizontal position, and elevation of pelvis caused no diminution in large quantity of blackened coagula which were constantly passing, while least movement increased discharge in a very great degree.

Since last delivery menses too seldom and very irregular, last time rather copious in consequence of unusual exertion.

at night dreamed she was ascending the stairs with a heavy load, and suddenly a clot of blood came away and the blood seemed to gush forth.

the alarm awakened her and she found that she was bleeding fast.

on following morning strength grealty reduced.

pulse could not be distinguished.

frequent fainting fits.

periodic pains with expulsion of clots of blood and between these attacks constant oozing of thin bright bloodfont.

After labor, pale, weak.

uterus distended, burning pains therein, hard, painful to least touch.

discharge of black, coagulated or brown, watery offensive-smelling blood.

throbbing, tearing pains in thighs extending down to toes.

pain worse from motion.

strong pulsations in umbilical region, which could be felt by the hand.

pulse at wrist weak and rapid.

frequent yawningfont.

Tumor increased rapidly, and increased fever.

pulse 130 to 150. tongue dry, dark-brown.

sordes on the teeth. vaginal secretions fetid.

frequent urgent micturition.

mucous dysentery with increased tenesmus.

countenance expressive of great suffering, under Secale, tumor discharged through the rectum, large quantity of dark, thick blood, patient gradually recovered.

Left thumb spasmodically drawn toward dorsum of hand, followed in a few minutes by cramping and flexure of rest of fingers toward palmar surface.

hands feel numb like velvet.

next day both hands became affected and after several days felt a tingling and stitches in legs, followed by heaviness of same, worse after walking, generally appearing while sitting, while cramps in hands always appear after using themfont.

Toes of right foot spasmodically drawn upwards, continuously during day and occasionally at night, causing a peculiar limping gait.

this cramp was accompanied by no pain, but by a very tiresome sensation rendering walking, particularly going up and down stairs, very difficult.

tendons running along dorsum of foot to toes were tense as wires and the corresponding muscles of leg larger and harder than normal.

now and then slight sensation of coldness in back and also a peculiar buzzing (formication) in spine.

Severe chill, from 4 A. M. to 10 A. M., in small of back, along spine.

during chill, shooting pains chiefly in legs and arms.

very thirsty during chill, little thirst during or after the fever.

slight sweat. mouth dry.

wants to drink continually.

violent nausea. vomiting great quantity of bile.

superficial congestion.

veins of extremities very full.

Right disk decidedly paler, with retina also of a paler tint. Left also paler (in one hour). Right disk paler.

on apparent inner side decidedly.

on outer side also a little. Left eye altogether a little paler (in one hour and twenty minutes). Retina and disks of both eyes decidedly pale, and this is especially observable in the right eye (in one hour). Retinae not quite so pale.

disks the same as before (in one hour and a half),.

Shortly the palpebrae began to swell, likewise the lips and fauces.

the tears flowed copiously.

the Schneiderian membrane seemed much stimulated, and there was coryza, great difficulty of breathing through the nose, and injection of the vessels of the conjunctiva. The lips and palpebrae began to puff, as if stung by a bee, and gradually assumed a livid appearance. The power of deglutition was nearly lost.

the voice became feeble.

she said her jaws were fixed, and shortly after it was with greatest difficulty that an answer of yes or no could be elicited. Previous to arriving at this point, she had complained of pain in every nerve, and a sensation of emptiness of the head,.

Tongue heavily coated white at noon, dry and brown at the tip (first day).

coated with a heavy brown fur and pointed at the end (second day).

heavily coated with a brownish fur, dry at the tip, edges stiff and swollen (third day).

dry and brown (fourth day).

dry, brown at the tip, and lead-colored at the root (fifth day).

covered with a brownish lead-colored coat in the centre, red at tip and edges (sixth day).

clean, very dry, and red at the tip (seventh day).

dry, glazed, and stiff, appearing as if baked, to the touch, with a hard crust formed on the surface (eighth day).

clear, red, and somewhat more moist than last night, pointed at tip (ninth day).

red and dry (tenth day).

red, dry, cracked, and bleeding (eleventh day),.

Skin hot, dry, and of a yellowish-brown color, resembling that of a mulatto (second and third days).

hot, dry, but not as dark as if was the day before (fourth day).

hot and dry, but of a better color, of a natural appearance on the feet and hands (sixth day).

soft and more natural to the touch, but still very yellow (ninth day).

yellow, soft, and moist (tenth day).

most and yellow (eleventh day),.

Her heart she described as having beat very rapidly for a long time, and her breathing as having been exceedingly laborious. After some hours the heart beat more quietly for a time, and then fell into inordinate activity as before.

intermitting in this manner throughout the day, during the earlier part of which she lay perfectly motionless, but without pain, recovering gradually towards evening the suspended animal function,.

Pulse depressed, very quick, and fluttering, ranging to 120 per minute (first day).

120, small and compressible (second day).

110, somewhat fuller than the day before, at 9 A.M.

100, quite full, at 7 P.M. (third day).

90, full, but easily compressed, at 8 P.M. (fifth day).

90, appears to have more volume, but easily compressed, at 9 A.M.

100, not as full and wiry, at 8 P.M. (sixth day).

100, small and feeble, at 9 A.M.

fuller with more volume, at 4 and 8 P.M. (seventh day).

92, full, at 8 P.M. (eighth day).

80, full, while quiet, but quick and very feeble while making the least exertion (ninth day).

80, moderately full, but easily compressed (tenth day).

80 to 90, weak and variable, at 10 A.M.

feeble, intermittent, ranging from 80 or 90, at 3 P.M. (eleventh day),.

After excessive lassitude, more or less protracted, and unaccompanied by fever, the extremities become painful, cold, and rigid.

benumbed and almost insensible, the limbs were yet capable of movement, though with difficulty.

the patients were afflicted with grievous internal pain, which was greatly increased by heat, whether of the bed or atmosphere, but abated somewhat when exposed to a cooler atmosphere, though even then it was scarcely tolerable.

the pain extended by degrees from the toes to the legs and thighs, and from the fingers to the arms and shoulders, till sphacelus supervening, the affected parts, dead and black, dropped from the trunk or the adjacent members,.

Urine scanty and dark-colored (first day).

urinary discharges of a dark wine, or "prune-juice" color (second day).

suppressed. on introducing the catheter, about a gill of dark prune-colored urine passed, which appeared to be full of gritty sediment, and emitted a very disagreeable odor (third day).

suppressed but on using the catheter, about a teaspoonful escaped, which was very dark and fetid.

a few drops falling on the linen stained dark brown.

only a few drops passed during the day (fourth day).

suppressed, passed three tablespoonfuls of urine by means of catheter, of a lighter color than formerly (fifth day).

procured a tablespoonful of urine by the use of the catheter, at 9 A.M.

passed a tablespoonful containing albumen, at 8 P.M. (sixth day).

scanty discharges from the bladder of a yellow color, and very fetid.

contained a large amount of albumen (seventh day).

thought we detected casts of the uriniferous tubes in the ounce of albuminous urine obtained by means of the catheter (eighth day).

albuminous, but of better color and larger quantity than at any time since the suppression commenced, containing mucus and albumen (ninth day).

kidneys more active. urine more copious, but albuminous, fetid (tenth day).

passed involuntarily for the first time in her sickness, more copious and containing blood and albumen (eleventh day),.

Violent paroxysms, consisting of contractions of the extremities, repeated at short intervals until the extremities became cold, stiff, and immovable, with violent pains in various muscles.

in some cases the attacks became tetanic, with trismus and opisthotonos, or even epilepsy, followed by weakness of memory.

the attacks frequently occurred suddenly in the night,.

Sudden vertigo and blindness.

the patients were deprived wholly or in part of their senses, fell to the ground, and suffered the most violent contraction of the joints, twitching of the limbs, trembling, and violent ineffectual efforts to vomit.

the elbows were pressed against the chest, the wrists flexed, the fingers doubled into the hands, the heels drawn upward toward the tendo Achillis, the toes bent under the sole of the foot, and frequently two strong men could not stretch out the limbs,.

Heat applied to any part of the body aggravated his pains.

his extreme aversion to warmth was very remarkable, and if on any cold day any additional covering was laid upon him while sleeping, he awakened almost instantly and threw it off.

he was generally found in the coldest weather lying in bed with only an old cloak thrown over him,.

Vomiting of dark-brown slimy mucus, and also of everything taken into the stomach (first day).

greater irritability of the stomach, and more difficulty of retaining food and medicine is observed at 8 P.M., than in morning (second day).

vomited twice (second night).

some nausea and vomiting, at 8 P.M. (fourth day).

nausea and vomiting of sour dark-green matter (fifth day).

vomited a pint of matter, in the morning, very sour, and of a dark-green color (sixth day).

vomited sour dark-green mucus, containing shreds of disorganized membrane (seventh day).

matter vomited contained shreds of mucous membrane (eighth day).

vomiting of dark bilious matter, at intervals of a few minutes.

constant nausea and vomiting.

matter vomited is of a dark-green color, containing mucus, bile, and shreds of membrane, in the evening (ninth day).

stomach can not retain even medicine or water (tenth day).

vomiting of blood, bile, membrane, and coffee-grounds matter.

inability to retain anything on the stomach.

the os was open as large as the middle finger.

the patient complained of excessive desire to urinate, and of labor pains, only relieved by wet bandages or by pressure upon the abdomen.

this lasted three days. She did not miscarry, though the os remained open during this period.

Secale Cornutum produces contraction of the un striped muscular fibers; hence a constringent feeling throughout the whole body. This produces an anaemic condition, coldness, numbness, petechiae, mortification, gangrene. A useful remedy for old people with shriveled skin - thin, scrawny old women. All the Secale Cornutum conditions are Better from cold; the whole body is pervaded by a sense of great heat. Hemorrhages; continued oozing; THIN, fetid, watery black blood. Debility, anxiety, emaciation, though appetite and thirst may be excessive. Facial and abdominal muscles twitch. Secale decreases the flow of pancreatic juice by raising the blood pressure ( Hinsdale).

First to thirtieth potency. Non-homeopathic use. If hemorrhages of the puerperium, after the uterus is entirely emptied, when it fails to contract satisfactorily and in secondary puerperal hemorrhage the result of incomplete involution of the uteru

Dusky, scrawny and heamorrhagic Numbness, insufferable tingling, crawling, twitching, gnawing or cramping; with stiffness; in single parts; starting in face or back; in limbs; in fingertips; after the pains, etc

Burnings; here and there, like fire

Dark, thin, foul or exhausting discharges Decomposition



Passive bleedings or discharges

Contracted arterioles

Tonic spasm

Mental weakness after spasms

Fear, depressed by; maniacal Sparks before eyes

Distorted or sunken countenance; blue rings under eyes

Wild look

Thirst; craves acids

Empty retching

Empty feeling in hypogastrium

Wants abdomen uncovered

Gushing, painless, watery, olive-green or bloody stools; with collapse

Bloody urine

Everything seems loose and open

Senile enuresis

Inert uterus, or bearing down with coldness

Contracted uterus; hour-glass contraction


Green lochia

Septic placenta


Gangrene of female organs

Leucorrhoea; brown, foul; continuous

Pains through chest on pressing spine

Cold limbs

Bluish fingers and toes

Cramps in hands, legs and feet

Fingers spread apart; bent backward or clenched; look water soaked

Boils with green pus

Blood blisters

Cold, dry, wrinkled or bluish skin, worse over affected part

Raynaud's disease

Foul, indolent ulcers

Twitching tremor or quiver in skin


Heat, as of sparks on skin


Cold or foul sweat; destroying shoes


Secale cornutum. Spurred Rye. Ergot of Rye. N. O. Fungi. Tincture of The fresh spurs collected just before harvest.

Abortion, threatened. After-pains. Albuminuria. Anus, incontinence of.

open. Asthenopia. Bladder, paralysis of. Boils. Carbuncles. Cataract. Chilblains. Cholera.

burning of. coldness of. Fibroma. Gangrene. Gastritis. Glands, swelling of.

suppuration of. Goître. Haematuria. Haemorrhages. Haemorrhagic diathesis. Heart, palpitation of. Hiccough. Hysteria. Impotence. Liver, enlargement of. Lochia, fetid. Lumbago. Menstruation, excessive. Metrorrhagia. Milk, suppressed. Miscarriage. Morvan's disease. Myelitis.

diffusa. Nails, degeneration of. Neuralgia. Night-sweats. Numbness. OEsophagitis. Ovaries, tumours of. Paralysis.

neuralgia of. prolapse.

Rye and grasses are apt to be affected with the Ergot disease in damp seasons, and when grown on damp, ill-drained lands.

If breeding cows are turned on pastures where infected grasses grow they are very liable to drop their calves.

Ergot has been known as a hastener of parturition from remote times.

Its other actions have been for the most part learned from the terrible epidemics of "Ergotism" which have occasionally devastated districts in which Rye infected with Ergot has been ground into flour and eaten by the population.

In general the sufferer retains a clear intellect and a good, even abnormally good, appetite to the last.

The nervous symptoms of Sec. are convulsive.

The body is at times rigid; at times rigidity alternates with relaxation.

Secale Cornutum is especially seen in the hands, which are either clenched or have the fingers spread widely apart (a keynote symptom).

The muscles of the face and abdomen twitch.

There is incontinence or retention of urine.

Spasmodic retching, the stomach is violently contracted.

Through the like action on the vaso-motor nerves there is first contraction and then dilatation of blood-vessels; the fingers turn bluish black.

Secale Cornutum stagnation leads to dry gangrene of the parts.

Sec. shrivels up the skin, makes it dry and harsh; sallow complexion.

It is therefore suited to─thin, scrawny women, feeble and of cachectic appearance; women of irritable, nervous temperament; of pale, sunken countenance.

To very old, decrepit persons.

On the other hand, it is also suited to Irritable, plethoric subjects.

Women of very lax muscular fibre; everything seems loose and open; no action, vessels flabby passive haemorrhages, copious flow of thin, black, watery blood.

For Sec. lessens the coagulating power of the blood. and produces a haemorrhagic diathesis; persistent, offensive bleeding.

Small wounds bleed persistently.

Purpura comes within this category.

One grand characteristic of Sec., which will determine its selection in many cases, is "agg.

By external heat." This applies to cholera, purpura, gangrene, and any condition which may present symptoms of Sec.

In cholera cases calling for Sec. the patient is cold, almost pulseless; there are spasmodic twitchings of muscles in various parts (especially spreading of fingers), eyes sunk, features pinched; surface harsh, shrivelled, dry, as though no moisture were left in the body.

Though cold to the touch, cannot bear to be covered.

In spite of this coldness, Sec. has burning among its characteristic sensations burning in all parts of the body as if sparks were falling on the patient.

Another characteristic sensation is numbness; tingling as if ants crawling all over, amel. from rubbing.

Secale Cornutum may accompany haemorrhages, loss of other fluids, debility, or skin affections.

In the later stages of ergotism there is anaesthesia.

The discharges are exhausting and offensive.

Diarrhoea is peculiar, involuntary; with wide-open anus.

The boils in which Sec. is indicated are small and painful, with green contents, mature very slowly, heal slowly, and are very weakening.

The eyes are affected in various ways Pustulous conjunctivitis; suppuration of cornea; dilated pupils, distortion, and strabismus; ptosis; suppressed tears.

Catarrh has been caused in many instances. "agg.

From warmth" will be the leading indication in many eye cases requiring Sec.

Exophthalmic goître has been cured with it; the heart being acted on by Sec. as other hollow viscera, and violent palpitation induced.

Sec. has a great affinity for the uterus, whether gravid or not.

Though its use in ordinary doses in obstetric practice is attended with danger, it may be used on its homoeopathic indications with perfect safety.

It is indicated ($51$) In threatened abortion, especially at the third month.

prolonged, bearing-down, forcing pains. (2) During labour when the pains are irregular, too weak, feeble, or ceasing.

everything seems loose and open, but there is no expulsive action.

fainting. (3) For after-pains when too long, too excessive.

or when there is hour-glass contraction of the uterus. (4) For suppression or non-appearance of the milk.

The menses of Sec. are irregular; copious, dark, fluid; accompanied by labour-like pains in abdomen; there maybe a continuous watery discharge of blood during the whole time between the periods.

Teste records this case A lady, 50, fat, very soft flesh, had flooding which nothing could stop.

After several useless attempts, Teste gave large doses of Sec. with scarcely any effect.

The patient asked for infinitesimal doses.

At that time Teste had no faith at all in infinitesimals, but he yielded to the patient's request, and gave one drop of the 6th.

The flooding ceased immediately and permanently.

Peculiar Sensations of Sec. are As if intoxicated while undressing.

As if eyes were spasmodically rotated.

As of a solid plug in nose.

As if tongue paralysed.

As if there were some resistance to be overcome in speech.

As of a heavy weight in stomach.

Region of stomach as if contracted.

Anus as if locked up. As if testes being drawn up to inguinal ring.

Uterus as if burnt. As if contents of uterus would fall forward.

As if soft air were creeping through back.

As if sacrum would be forced out.

As if something alive creeping under skin.

As if fingers asleep. As if limbs had been a long time in hot water.

As if sparks of fire falling on different parts.

As if mice creeping under skin.

Fuzzy feeling in limbs.

Sec. is indicated in Suppressions tears; lochia; milk; sweat.

Thirst with dry mouth or burning.

Desires lemonade and sour things.

Averse to fat and meat.

The symptoms are agg. By touch. amel.

Lying doubled up in bed.

Motion and any exertion agg.

Walking = giddiness. Many symptoms (cramps, twitchings) agg. night.

Sinking spells 3 a.m. Open air amel.

Wants to be fanned. Warm applications agg.

Warm drink agg. Wet bandages amel. labour pains.

Cold applications amel. agg.

After eating. All symptoms agg. just before menses.

The right side is predominantly affected.

Ergot. A nosode from the rye, called a parasite. No Proving.*

* *

* A collection of the monographs of epidemics, supposed to have been caused in Germany and France, principally by the ergot and other mixtures which spoil the bread, was made in 1825, by C. Hering, and left the next year, on his departure for Surinam, with Trinks, who had it completed by some of his assistants, and published. Later addition are mostly cases of poisoning.

The best provers of Secale, those who are most susceptible to its action, are scrawny people, and they are the ones who will most likely need it as their curative remedy.

Aspect Of course, it is not necessarily contra-indicated in fat people. Certain constitutions are mentioned in connection with a remedy as being suited to it, but it must not be inferred that no action will result in others when the symptoms agree. Scrawny people are especially related to Secale.

Emaciated, withered, wrinkled, unhealthy appearance of the skin; purplish, bluish skin, general or in spots; purplish I spots on withered skin, especially where the circulation is feeble as on the back of the hands and feet and on the tibia.

These parts become numb, tingle and wither. The extremities prickle, burn, and tingle; creeping and crawling, as of insects under the skin, as if between the skin and the flesh; numb, dead, wooden sensation in the fingers and especially in the toes.

The toes become black, gangrenous. A senile withering, such as is found in feeble old people; the blood-vessels close up; no blood goes to the toes and they become numb and black, devoid of sensation. Hence, Secale improves the circulation of the aged and postpones senile gangrene.

Burning is a feature of Secale Cornutum; the skin burns; the extremities burn, sensation of burning when the parts feel cold to the touch and really are cold, a sensation of heat with coldness.

Burning, especially of internal parts. Dryness with burning; burning in the stomach and bowels; dryness and burning in the mouth and throat, the nose and air passages; burning in the lungs.

Secale Cornutum produces ulceration even to sloughing. Old ulcers take on a strange, withered appearance.

dryness with no, granulations.

a shiny, blackish aspect and all at once blackish granulations shoot out, indolent, and finally forming a black sphacelus which slowly separates.

the part is dry. there is no discharge except now and then a little bleeding of black blood.

Oozing of black, liquid blood, oozing when there is no inflammation; nose-bleed of dark, venous, offensive, fluid blood, bleeding from the throat, lungs, bladder, and rectum, of dark blood; urine like ink.

Women Prolonged uterine haemorrhage so that one menstrual nisus runs into another; withered subjects; considerable flow on the first day, fluid, and blackish; this goes on for a couple of weeks and then a dark watery flow comes on which lasts until the next period.

Then comes the thick, black, fluid, horribly offensive flow again. Such a state is found in the woman who has taken ergot to produce abortion, or in sensitive women who have been dosed with it to facilitate delivery. Of course, if the woman is not sensitive you will not get the lingering provings,

Some women are so insane that though they die they will get rid of their offspring. On all hands women say,

"I have had no health since I aborted."

They have placed themselves beyond the help of the physician and the ergot will shorten their lives many years unless they are fortunate enough to have careful prescribing continuously while they live.

Modalities The general constitutional state is aggravated from heat; there are only a few exceptions to this.

Wants cold though the limbs are cold as ice, wants to be uncovered, wants the windows open; a patient with hemorrhages wants the covers off though the room is cold. A patient with ulcers wants to be uncovered; in inflammatory condition of the stomach and bowels, wants the abdomen uncovered.

At times there is a lingering state of heat of the skin and the patient wants to be covered up; there are also sharp, stinging neuralgic pains, which burn like fire and cut like a knife and are relieved by the application of beat; headache worse in cold air.

But the general state is ameliorated from uncovering, in a cold room, and from cold air blowing on the patient.

Violent inflammation of any part of the body; gangrenous pneumonia; gastritis; peritonitis; inflammation of the uterus and ovaries. In inflammatory conditions it competes with Arsenicum Album Ars

The symptoms are so nearly alike in both that it is difficult to differentiate.

both have violently distended abdomen.

tympanites. burning like coals of fire.

violent thirst. extreme sensitiveness and tenderness to touch, so that motion or jar is unbearable.

vomiting of blood. expulsion of blood-clots.

horrible, offensive, bloody discharge from the bowels.

but they are different in the generals. Arsenicum Album Ars wants to be covered up, to be kept warm, to have hot applications, either wet or dry, while Secale wants to be uncovered, wants the cold air.

Convulsions of single parts or of the whole muscular system; opisthotonos; cramps in the calves, thighs, soles of the feet, and hands, hysterical contractures, a hysterical diathesis.

Convulsions begin in the face. Active manias with great excitement; exposes her body and tears at the genitals; puts her finger in the vagina and scratches until the lips bleed; all idea of modesty lost.

The spasms, nervous, and mental symptoms are worse while she is flowing, so that a puerperal convulsion comes on in the midst of a hemorrhage.

From the hemorrhagic tendency and the ability to destroy the red blood corpuscle, there is anemia. The face looks like dried beef, wrinkled, shrivelled, scrawny, as if it had not been washed; as if grey dirt had dried on the skin, and this especially on the extremities a dirty, grey appearance.

Catarrhal affections of all mucus membranes; they are dry and bleed; blood oozes from the catarrhal surfaces, liquid, black, and offensive, coagulating slowly or not at all.

"Nosebleed, blood dark, runs continually, with great prostration, small thread-like pulse; in old people or drunkards; of young women; from debility."

Those poisoned by ergot become victims of opacity of the lens as in senile debility; cataract of old persons.

The withered scrawny person with tendency to ulcerations, unhealthy skin and aggravation from heat, is striking in both acute and chronic states.

Chronic diarrhoea exhaustive, watery discharges, cholera. It is related to Camphora Camphor, Scrawny people take cholera, skin cold and blue; better from cold. Violent and continued thirst.

Diarrhoea and hemorrhages are likely to come together; diarrhoea of bloody water or dark liquid blood.

Large doses produce such contractures of the uterus that its contents are expelled and an exhausting hemorrhage follows; expulsion of large clots and in the early stages mixed with some red blood, but the most striking feature is liquid, black discharge.

"Asiatic cholera with collapse, sunken, distorted face, particularly the mouth, crawling sensation as of ants."

Paretic condition; paralysis of lower extremities; of one side; of one arm or one leg; paralysis of the upper extremities with tingling, numbness, and prickling. Numbness and burning down the whole length of the spine; general emaciation or only of diseased part.

Eruptions, abscesses, boils carbuncles; green pus discharged; a green, purplish appearance; boils small with green contents, mature and heal slowly.

Establishes sterility; so weak is the uterus that it can never hold the foetus, hence the value in sterility and repeated abortions.

Dwindling of the mammae. Absence of milk after confinement.

"Thin, scrawny children with shrivelled skin, spasmodic twitchings, sudden cries, feverishness."

Purpura hoemorrhagica. Paralysis of the extremities. Spinal irritation. Cachectic females with rough skin, pustules tending to gangrene.

Passive haemorrhage, everything open and loose, no action, in thin, scrawny, cachectic women.

Great coldness (objective) of the surface, yet the patient cannot bear to be covered.

Numbness, crawling and paralysis; formication as of mice creeping there, all parts of body.

Secale cornutum is a remedy capable of great good, but is perhaps, as much misused as Quinine. Secale Cornutum's power to contract the uterus is undoubted, and for this reason it is often given when other remedies would do better. It has power to control haemorrhages, that few other remedies, if any, can surpass. It is said to do this by contracting the capillaries. But we must remember that other remedies control haemorrhages, and whether they do it by contracting the capillaries, by their action upon the blood itself or other specific action, makes no difference, so long as they control it. Some physicians are always giving Ergot in post partum haemorrhages on this contracted theory, without ever thinking of anything else.

They always give it in material doses to get, as they term it, the physiological effect. I have never, in a practice of thirty-five years, used it in this way, but have always been able to control such haemorrhages. Secale is not often indicated in active post-partum haemorrhages. If there is a tendency to passive haemorrhage, everything open and loose, no action, in thin, scrawny, cachectic women (muscles flabby), there is no remedy like it, and the potencies are much better than the tincture or wine of Ergot in massive doses. This is also true in menorrhagias and metrorrhagias unconnected with pregnancy. The blood is dark, liquid and flowing worse on the slightest motion.

The constitution, temperament and age of the patient are of great importance, for it is particularly adapted to feeble, thin, scrawny, cachectic women of lax muscular fibre, subject to passive haemorrhages from all outlets of the body; also old, decrepit persons.

Secale Cornutum (Secale) is often abused on account of its power to produce muscular contractions of the womb. Now in regard to this as with haemorrhages, it is capable of doing all that it ought to be called upon to do, in the potencies.

I fully agree with Cowperthwaite, who says "To give it in parturition to hasten delivery, as is the practice of the old school, is simply inexcusable." on the other hand, I agree with Dr. H. N. Guernsey, "that it is useful when labor pains are weak, suppressed or distressing, in weak, cachectic women; in the 200th dilution," and have verified it beyond question.

The practice of giving the fluid extract in such cases, as is done by some physicians calling themselves homoeopathic, ought to be sufficient cause for expelling them from a homoeopathic society. It seems to me to be confession of either inexcusable laziness or ignorance.

We have a long list of remedies of undoubted value for weak labor pains with specific indications for their use, and when so indicated they are more efficacious and less dangerous than Secale in massive doses of fluid extract with no other indications than uncontracted uterus or weak pains. The men who prate learnedly of getting the physiological effects of Secale in massive doses had better ask themselves if the same result gotten with the potentized remedy homoeopathically applied, is not just as much in accordance with the physiological law, and much more scientific from a homoeopathic standpoint. Weak pains remedied by the indicated homoeopathic drug bring on natural labor, while large doses for the same purpose of an unindicated one do not and never can produce natural labor. It is nothing more or less than drug poisoning.

Here is one symptom of Secale that is of inestimable value "Great coldness (objective) of the surface yet the patient cannot bear to be covered." This is oftenest found in cholera and cholera infantum; but it is also found in senile gangrene.

The feet and toes may be objectively as cold as an iron wedge, but the patient is distressed beyond endurance by having them covered. I saw one marked case of this kind. All the toes were attacked with dry gangrene. A few doses of Secale (high) afforded great relief, and checked the progress of the disease for a long time.

Camphora Camphora has the same symptom in a marked degree in choleraic disease. Camphora Camphora seems to be most efficacious for the first stage or early collapse in the course of the disease, before the discharges have become offensive, putrid or dark colored. Secale has burning in the feet (Sulphur Sulphur) and cramps in the calves (Sulphur Sulphur).

If, however, we should prescribe on this alone it would make no difference which we prescribed, but they are very unlike in their entirety. Sulphur Sulphur does not have the degree of collapse of Secale, nor the icy coldness of surface with subjective burning. So we see the folly of one symptom prescribing after all.

We must have the keynote symptom, of course, but it must harmonize with the rest of the case. Secale has "burning of all parts of the body, as if sparks were falling on them." It also has numbness, crawling and paralysis of the extremities. This is due to its action on the spinal chord. In addition to the coldness of the skin already noticed, we must state that the skin looks dry, wrinkled and is insensible often, or there may be much formication under, as if mice were creeping there.








Adapted to women of thin, scrawny, feeble, cachectic appearance; irritable, nervous temperament; pale, sunken countenance.

Very old, decrepit, feeble persons.

Women of very lax muscular fibre; everything seems loose and open; no action, vessels flabby; passive hemorrhages, copious flow of thin, back, watery blood; the corpuscles are destroyed.

Hemorrhagic diathesis; the slightest wound causes bleeding for weeks (Lachesis Lach., Phosphorus Phos.); discharge of sanious liquid blood with a strong tendency to putrescence; tingling in the limbs and great debility, especially when the weakness is not caused by previous loss of fluids.

Leucorrhea; green, brown, offensive.

Boils small, painful with green contents, mature very slowly and heal in the same manner; very debilitating.

Face pale, pinched, ashy, sunken, hippocratic; drawn, with sunken eyes; blue rings around eyes.

Unnatural, ravenous appetite; even with exhausting diarrhea; craves acids, lemonade.

Diarrhea profuse, watery, putrid, brown; discharged with great force (Gamb., Crot.); very exhausting; painless, involuntary; anus wide open (Apis Mel Apis, Phosphorus Phos.).

Enuresis of old people; urine pale, watery, or bloody; urine suppressed.

Burning, in all parts of the body, as if sparks of fire were falling on the patient (Arsenicum Album Ars.).

Gangrene; dry, senile, worse from external heat.

Large ecchymoses; blood blisters; often commencement of gangrene.

Collapse in cholera diseases; skin cold, yet cannot bear to be covered (Camphora Camph.).

The skin feels cold to the touch, yet the patient cannot tolerate covering; icy coldness of extremities.

Menses irregular; copious, dark fluid; with pressing, laborlike pains in abdomen; continuous discharge of watery blood until next period.

Threatened abortion especially at third month (Sab.); prolonged, bearing down, forcing pains.

During labor pains irregular; too weak; feeble or ceasing; everything seems loose and open but no expulsive action; fainting.

After pains too long; too painful; hour-glass contraction.

Suppression of milk; in thin, scrawny, exhausted women; the breasts do not properly fill.

Pulse small, rapid, contracted and often intermittentp


1font Mrs. L. M. Hayes, with the 200th. This prover knew the potency but not the drug. She was perfectly convinced that in the 200th potency no drug was capable of producing medicinal symptoms on the healthy, and persisted in repeating her experiments to verify or disprove former results. Took November 4th, six drops every other day for a week. November 17th, took six drops twice a day for a week. January 5th, took fifteen drops every day for a week. March, 1st, took fifteen drops every morning for three days.

2font Miss R. C. Wilder, took six drops, 30th potency, in morning of November 5th, 8th, 12th, 15th.

3font H. B. Reynolds, took one drachm of 2d potency, in repeated doses.

4font J. S. Campbell, took several doses of 2d potency.

5font F. W. Rogers, took one drachm of 200th potency, a dose twice a day for two weeks. 6font Mrs. M. T. Hathaway, repeated doses of 200th potency.

7font D. M. Finley, 100th potency; repeated the proving four times with results each time.

8font Miss H. M. Swathel, took 200th potency, from March 1st to April 23rd, two or three times a day. Took 100th potency from May 2nd to May 15th, once or twice daily.

9font G. D. Green, took 2d potency for two weeks.

10font C. S. Erswell, took 100th potency, one drachm, in daily doses for two weeks.

11font E. H. Pond, took 30th Potency.

12font E. C. Watts, took 30th potency daily for a weekp

Since March, 1880, the drug was given out to seventy-two volunteers, as follows

Second potency to 16 provers.

Third potency to 4 provers.

Sixth potency to 17 provers.

Thirtieth potency to 13 provers.

Sixtieth potency to 5 provers.

One hundredth potency to 6 provers.

Two hundredth potency to 8 provers.

Blanks potency to 3 proversp

The blanks were given to those whose health, on examination, was not deemed sufficiently good to warrant a reliable proving, only one of whom (a young man who afterwards died of albuminuria) obtained or returned any resultsp


So far as possible, every prover was examined as to health and personal qualifications; and questioned or cross-questioned on the recorded results.

Provers were directed to follow the rules laid down by Dunham for proving a drug.

No person knew what she or he was takingp


Adam Lonicer, of Frankfort, about the middle of the 16th century, is the first botanical writer to notice Ergot, and soon after Thalius speaks of it as used "ad sistendum sanguinemfont"

In 1623, Caspar Bauhin mentions it under the name of Secale luxurians, and in 1639 the English botanist Ray alludes to its medicinal properties.


Hamilton sums up the conflicting views entertained by various writers as follows

afont "Some regard Ergot as a fungus growing between the glumes of grasses, in the place of the ovary (hence Léveille calls it Spacelia segetum).

bfont "Some regard Ergot as a diseased condition of the ovary or seed.

cfont "Some have supposed that ordinary morbific causes (such as moisture combined with warmth) were sufficient to give rise to this diseased condition of the grain.

dfont "Some have ascribed the disease to the attack of insects or other animals.

efont "Come, dissatisfied with the previously assigned causes of the disease, have been content with declaring Ergot to be a disease, but without specifying the circumstances which induce it."

Fluckiger and Hanbury state, "That the tissue of the seed of the rye, in the process of development, does not undergo a transformation, but is simply destroyedfont"

At certain points small, orbicular patches of the rind fold themselves back, and gradually throw out little white heads. These increase in size whilst the outer layers of the neighbouring tissue gradually lose their firmness and become soft and rather granular, at the same time that the cells, of which they are made up, become empty and extended. In the interior of Ergot, the cells retain their oil drops unaltered. The heads assume a grayish-yellow color, changing to purple, and finally after some weeks stretch themselves towards the light on slender, shining stalks, of a pale, Viola Odorata violet color. The stalks often attain an inch in length with a thickness of about half a line. Fluckiger further says "Ergot of rye collected by myself in August, placed upon earth in a garden-pot and left in the open air unprotected through the winter, began to develop the Claviceps on the 20th of March."

Hering calls it an undetermined fungus, and from the doubtful position it has so long held in the world of science classes it, not without some reason, as a "Nosode"; and when a doubtful point in Materia Medica is to be solved, the opinion of the venerated and scientific Hering is deserving of some consideration.

Nosode, he says "Is the general term given to the alcoholic extracts of morbid productions, foolishly called isopathic remedies. The most useful and fully proved are Lyssin (Hydrophobinum) Hydrophobinum and Psorinum Psorinum. To these "Nosodes" belong the Ustilago Maydis Ustilago maidis, the Secale cornutum, the fungus of the Solanum Tuberosum potato, the Ambra Grisea ambra of the potfish, anthracin, vaccinin, variolin, etc., etc. The sneering remarks of Trinks and others in 1826 against Sepia Sepia and the ignorant opposition to Lachesis Lachesis have sunken into oblivion during the succeeding score of years. All the condemming remarks against the Lyssin (Hydrophobinum) Hydrophobinum, Psorinum Psorinum and other "Nosodes" will meet the same fate. We can afford to wait."


For homeopathic use the Ergot of rye should always be prepared fresh, as it is fed on by a small acarus which destroys the interior of the grain, leaving it a mere shell.

Ergot kept in stock longer than a year should always be rejected on this accountp


Among the writings of the ancients there is no distinct notice to be found of Ergot.

In 1089 the French historian, Sigebert, refers to an epidemic in the following passage

"A pestilent year, especially in the western parts of Lorraine, where many persons became putrid, in consequence of their inward parts being consumed by St. Anthony's fire. Their limbs were rotten and became black like coal. They either perished miserably or, deprived of their putrid hands and feet, were reserved for a more miserable life. Moreover, many cripples were afflicted with contraction of the sinews." An epidemic disease in Hessia in 1596 first attracted the attention of the medical profession to Ergot as a cause. Rathlaw, a Dutch accoucheur, employed it m 1747, but it was not until thirty years later, 1777, that the essays of Desgranges, and especially those of Stearns and Prescott in the United States, that its medicinal properties became known.

From time to time a number of monographs giving a more or less accurate description of the various epidemics supposed to have been caused chiefly by Ergot and other adulterations in France, Germany and Switzerland have appeared. In 1825, the year previous to his departure for South America, Hering made a collection of these monographs which he left with Trinks, who had it completed by one of his assistant and published. These comprise the first 80 of the 170 authorities of the encyclopaedia, taken from Hartlaub and Trinks. The later additions are chiefly toxicological and clinical.

Dr. R. B. Johnstone, of Pittsford, N. Y., writes


March 6, 1885. - Took a powder (Secale 200) every morning and at night on retiring, for three days, then at night only, for a week.

March 9th. - A sore spot felt on back part of base of tongue, left side, as though a "canker sore" were making its appearance; it was not felt in day time and passed away after a few days.

March 10th and 11th. - A slight frontal headache and some mental confusion, but not very troublesome. Sore spot on base of tongue, right side.

March 13th. - Spots with a sore bruised feeling appeared about and below the left knee. On looking found a swollen patch about the size of a Argentum Metallicum silver half dollar, of a purple red color. Towards evening three or four similar spots appeared further down the leg, about the top of the shoe, so sore could scarcely bear the touch of the shoe, and attended with violent itching, but were so extremely sore could not scratch them, and when touched gave me a faint, sick feeling.

March 14th. - Headache and confusion more pronounced, and chiefly in frontal region. Three or four spots appeared on right leg below the knee, with violent itching and the same sore bruised feeling.

March 15th. - An eruption in the form of a rash or small pustules appeared on the face, left side chiefly, very sore and sensitive to touch. It would begin in fine points like the prick of a pin or the sting of an insect and gradually increasing in size to small pustule as large as a pea. Felt like the spots on the legs, with the same sore, bruised feeling in the skin of face and neck. There were twenty-eight small pustules on left side of face and neck.

April 5th. - The eruption on face, neck and shoulders gradually disappeared, but left discolored, ecchymosed spots and patches like the remains of an old bruise for several weeks, especially on lower leg.

April 18th. - Menses appeared on time, very profuse for the first three or four days, accompanied by a good deal of pain and an uneasy sore feeling through the pelvis (much more than usual), but an unusual amount of pain for a week before the menses. Flow darker much more profuse (formerly profuse for one day) for four days. Considerable clotting. The flow continued for ten days, a circumstance which never occurred before. Vertigo during entire menstrual period, with inclination to fall forwards.