Physostigma

▲   GENERAL

General

Physostigma and its active principle, Eserine, form a valuable addition to Materia Medica. Stimulates heart, raises blood pressure, and increases peristalsis. Causes contraction of the pupil and of the ciliary muscles. Induces a condition of short-sightedness. Spinal irritation, loss of motility, prostration, with very sensitive vertebrae. Fibrillary tremors. Rigidity of muscles; paralysis. Depresses the motor and reflex activity of the cord and causes loss of sensibility to pain, muscular weakness, followed by complete paralysis, although muscular contractility is not impaired. Paralysis and tremors, chorea. Meningeal irritation, with rigidity of muscles. TETANUS and trismus. Poly myelitis anterior. Eserine is used locally to produce contraction of pupil.

Dose

Third potency. The neutral sulphate of Eserine is instilled into the eye, from one-half to four grains to one ounce distilled water, to induce Contraction of pupil, in mydriasis, injuries to the eye, iritis, corneal ulcers

▲   RELATIONSHIPS

Relationships

Compare: Eserine - the alkaloid of Physostigma - (slows action of heart and increases arterial tension; in ciliary spasm and spasmodic Astigmatism due to irregular action of ciliary muscles; blepharo-spasms; Pupils contracted. Twitching of lids, soreness of eyeballs, blurring of vision After using eyes, pains around eyes and head). Used locally to contract the pupil. ESERINE contracts the pupils dilated by Atropine, but not those dilated by Gelsemium Sempervirens ^Gelsemium. Internally 6X. Eserin salicylate (post-operative intestinal paralysis; meteorism. Hypodermically 1/60-1/40 gr).

Compare

Compare also: Muscarin; Conium Mac ^Conium; Curare ^Curare; Gelsemium Sempervirens ^Gels.; Thebainum (tetanus); Piperazinum - (Uric acid conditions. Pruritus. Gout and urinary calculi. Constant backache. Skin dry, urine scanty. Rheumatic arthritis. Give one grain daily in carbonated water. First and second decimal trituration three times a day.)

Antidotes

Antidote: Atropia Sulphurica ^Atropia. In full medicinal doses will relieve most of the effects of Physostigmine.

▲   MIND

Mind

Aversions, dislikes; reading

Behaviour

foolish behaviour

habits; boring fingers in ear

Dazed

afternoon

Delusions, imaginations, hallucinations, illusions

environment and surroundings; objects too numerous in room

visions or presence of phantoms, figures, people; spectres, ghosts, spirits

As if in a dream

Emotions, feelings, attitude, disposition

cheerful, happy

indifference, apathy, etc.; to business affairs

Intellectual faculties

bright, intelligent, clear; abundant ideas, clearness of mind; during chill

impaired thinking; difficulty concentrating

impaired thinking; confusion

impaired thinking; dull, sluggish

morning

while walking

thoughts wandering

while studying

ideas; abundant ideas, clearness of mind; during chill

Insanity

Insecure, uncertain, scared

anxiety; about friends at home

anxiety; during sleep (see dreams)

fear; of insanity

night

fear; might do mischief, night on waking

frightened easily; starting, startled; easily

frightened easily; starting, startled; recovering consciousness

Memory; active memory

Perception

incorrect judge of size; frame seems lessened

incorrect judge of size; things appear smaller

Preoccupied; counting continually

Restlessness, nervousness

morning

evening

night

Talking, conversation; speech; slow

Thoughts (see preoccupied); frightful thoughts

persistent (see delusions)

▲   VERTIGO, DIZZINESS

Vertigo

Constant pain on top; vertigo, with constrictive feeling of head

Night

After bathing

After eating; on rising from dinner

From movement

While reading

While walking

when walking down

stairs

while in the open air

▲   HEAD

Head

Spastic conditions of the face-muscles.

Brain

inflammation of brain

brain feels loose

Congestion (see pulsation); fullness

fullness

afternoon

fullness; forehead

afternoon

Constriction, tension (see also pulling, pressing)

like band or hoop

as of a tight hat

forehead

across

Hot

afternoon

evening

forehead

Movements in head; rolling

Movements of head

falling (see heaviness); forward

trembling; extending to pit of stomach

Sensation of numbness

temples

Pulsating

afternoon

back of head (occiput)

temples

Weakness; extending to lower extremities, as though paralysed

Headache

Pain over orbits; Cannot bear to raise eyelids

Heaviness (see pain

pressing)

pressing); morning

pressing); dull

pressing); from movement

Pain, headache

morning

on waking

morning; from 6 a.m.; until 10 a.m.

afternoon; 1 p.m.

afternoon; 2 p.m.

afternoon; 4 p.m.

evening

8 p.m.

10 p.m.

affected by certain foods and drinks (improved, brought on or aggravated); after drinking milk

eyes and vision (affecting or affected by); from straining eyes

living in a damp house

from exertion; when trying to keep awake

while lying down

lies with head low

mental exertion

certain movements; rising (see morning, noon, night, etc., on rising, also movement; raising head); from lying

certain movements; rising (see morning, noon, night, etc., on rising, also movement; raising head); from sitting

from certain movements; movement in general

from certain movements; from stooping

from certain movements; turning head

rubbing head

sudden pain or sudden increase of pain; pain comes on suddenly

aching deep in brain

on waking

in forehead

left side

afternoon; 4 p.m.

evening

night

on movement

pressure

while reading

after rising

rubbing

while walking

while walking in open air

extending to other parts; back of head (occiput)

extending to other parts; temples

above eyes

above eyes; above right

above eyes; afternoon; 1 p.m.

middle

back of head (occiput)

late morning

while walking

sides

sides; left

sides; from noise

temples

movement

pulsating; while reading

and forehead

top of head (vertex)

afternoon

pressure

burning

morning

evening

forehead

forehead; morning

bursting

pressing (see bursting, pulling); dull

pressing (see bursting, pulling); from pressure of hat

pressing (see bursting, pulling); outward

pressing (see bursting, pulling); as if brain pressing; outward

pressing (see bursting, pulling); temples

outward

pressing (see bursting, pulling); top of head (vertex)

outward

shooting (see cutting, piercing, stabbing, shocks, stitches, etc.); rising

shooting (see cutting, piercing, stabbing, shocks, stitches, etc.); while walking

shooting (see cutting, piercing, stabbing, shocks, stitches, etc.); side

shooting (see cutting, piercing, stabbing, shocks, stitches, etc.); temples

sore bruised, sensitive to pressure; in brain

sore bruised, sensitive to pressure; temples

daytime

Scalp

Skin and scalp

perspiration; scalp; with headache

perspiration; forehead; morning

during stool

perspiration; forehead; warm

▲   EYES

Eyes

Night-blindness (Opposite: Bothrops Lanceolatus ^Bothrops); photophobia; Contraction of pupils; twitching of ocular muscles

Lagophthalmus

Muscae volitantes; flashes of light; partial blindness

Glaucoma; paresis of accommodation; astigmatism

Profuse lachrymation

Spasm of ciliary muscle, with irritability after using eyes

increasing myopia

Post-diphtheritic paralysis of eye and accommodation muscles.

Lids

dislikes to open eyes, fears it will aggrevate headache

eyes closed; dislikes to open them, fears it will aggrevate headache

Discharges of mucus or pus

Sensation of fullness

Heaviness; lids

Pain

late morning

11 a.m.

afternoon

2 p.m.

6 p.m.

evening

while reading

on movement of eyes

sideways

when using eyes; when reading

extending to other parts; backward

extending to other parts; to temples

burning, smarting, gnawing, biting

morning

late morning

pulling

afternoon

evening

pressing

sore, bruised, tender

moving the eyes

lids

stitching, sudden, sharp

right

movement

pressure

Paralysis

lids; upper; right

of muscles of eyeball; ciliary (muscles of iris)

Pulsation in eyes

Pupils

contracted

alternately contracted and dilated in the same light

dilated

Spasms; muscles which focus eye

Swellings

sensation of swelling

Tension

lids; on closing

Twitching; lids

Weak

while reading

Vision

Accommodation, movement of eyeball

defective

action too great

diminished

Blurred

letters

Colours and shapes in front of eyes

colours; black; spots; floating (aka muscae volitantes or spiders)

colours; dark; serpent-like waves

colours; dark; worms

flashes

lightning

Confused vision

Objects seem distorted

objects seem large

objects seem nearer

Dazzling; trembling objects (see dazzling)

Dim

descending stairs

after diphtheria

distant objects

while writing

Double vision

Exertion of vision

Flickering

Foggy; walking

Long-sighted (near objects blurred)

Lost vision, blindness; writing

Moving; letters

Short-sightedness

▲   EARS

Ear

Sensation of fullness

Heat

Itching; like insects crawling on skin

Noises in ear

evening; 7 p.m.

ringing; evening; 7 p.m.

singing

night; after lying down

steam escaping

like steam escaping

Pain

afternoon

3 p.m.

evening; 7 p.m.

boring with finger

while writing

behind ear

inside (in ear canal)

boring pain in ear; evening

boring pain in ear; when boring into ear with finger

stitching, sudden, sharp; afternoon; 3 p.m.

stitching, sudden, sharp; evening; 6 p.m.

Pulsation

evening

Skin; abscess; behind

Stopped sensation

Hearing

Impaired

right

late morning

lasting till 8 p.m.

evening; 9 p.m.

Too sensitive

▲   FACE

Face

Contraction (see distortion)

Convulsions, spasms

Expression; sleepy

Heat

afternoon

afternoon; 2 p.m.

Motions of jaw; lockjaw

Pain; jaw; lower jaw

Skin

discoloration; bluish; with convulsions

discoloration; pale

discoloration; red

afternoon

on rising

Twitching; around mouth

▲   NOSE

Nose

Fever-blisters around nostrils.

Movement of wings of nose; widened nostrils

Numbness

Pain; burning, smarting

Twitching (see face)

Discharge

Fluent coryza; burning and tingling of nostrils; nose stuffed and hot

Sneezing

▲   MOUTH

Mouth

Feeling as if a ball came up throat.

Odour (halitosis, bad breath); offensive; morning

Saliva

Saliva; frothy

Tongue

Tongue feels sore on tip

Pain

sore; tongue; sides; left

sore; tongue; tip

stitching, sudden, sharp; tongue

Prickling; tongue; tip

Tongue

movement of tongue; difficult (see protruded)

stiff tongue

▲   THROAT

Throat

Strong heart-pulsation felt in throat.

Choking, constricting

evening

Sensation of something in throat

bone (see pain, as of a splinter)

lump; rising sensation

Fullness

Mucus

evening; 6 p.m.

Pain

burning; tonsils

sore

afternoon

as from a splinter

Swallowing; impossible

Tickling in the air passages; larynx

External throat

pain; sides

pain; sides; on movement

pain; sides; rheumatic

pain; sides; on waking

pulsation; artery

stiffness of sides

▲   CHEST

Chest

Heart; Feeble pulse; palpitation; spasmodic action, with feeling of pulsation through the whole body

Fluttering of heart felt in throat

Fatty degeneration ( Cup-ac.)

Constriction, tension

Heart

palpitations

palpitations; while lying down; side; left

palpitations; tumultuous, violent, intense

Movements in and of chest; trembling; heart (see fluttering)

Pain

arm pit

sides

aching; arm pit

sore, bruised; collar bone

Pulse

Beats of heart distinctly perceptible in chest and head

Respiration

Difficult (dyspnea)

night

10 p.m.

in open air

Sighing

Hiccup

Stomach; hiccup; evening; 5 to 8 p.m.

▲   COUGH

Cough

Evening; 6 p.m.

▲   EXPECTORATION

Expectoration

White

Mucous

Watery

▲   BACK AND NECK

Back and neck

Pain

sore, bruised, beaten; neck

sore, bruised, beaten; lumbar (lower half of back)

Neck

neck

pulling; neck

Stiffness

neck

neck; on waking

Back

Coldness

on movement

travelling up the back

Heat

evening

extending down the back

Inflammation; spinal cord

Numbness

Pain

evening

night

travels downwards

in women

during period

dorsal (shoulder level); hindering breathing

dorsal (shoulder level); shoulder blades; right; under shoulder blade

lumbar (lower half of back); exertion

sacrum (base of spine)

during movement

spine; irritation

spine; extending to other parts; down

aching

evening

night

during period

dorsal (shoulder level); shoulder blades; under them

lumbar (lower half of back)

with rigidness

lumbar (lower half of back); on physical exertion

pressing; during period

Skin; out-breaks on skin; like flea bites

Spasms

Twitching

Weakness (tired feeling, in spine)

lumbar (lower half of back); after exertion

▲   ABDOMEN

Abdomen

Stomach; Great pain immediately after eating

Sensitive to pressure in epigastric region

Pain extends into chest and down arms

Gastralgia.; chronic constipation.

Sensation as if diarrhoea would come on

Emptiness

Heat

late morning

Noises from abdomen

gurgling

rumbling; afternoon; 4 p.m.

Pain

afternoon; 4 p.m.

evening

as if diarrhoea would come on

while lying down; lying on back

lying down; lying on side; lying on right side

lying down

during stool

extending across abdomen

region of hip; around hip; right

region of hip; around hip; eating

region of hip; around hip; lying on left side

region of hip; around hip; pressure

region of hip; around hip; while walking in open air

groin region

right then left

navel; region of navel

cramping, griping; while lying down; on back

cramping, griping; while lying down; on right side

cramping, griping; on movement

pressing; before stool

stabbing, piercing; behind lower ribs

sore, bruised, tenderness, etc.; behind lower ribs; movement

sore, bruised, tenderness, etc.; lower part of abdomen

sudden, sharp (sticking, etc.)

groin region; extending to other parts; testicle

sides

Swelling; groin region; 8 p.m.

Bladder

fullness

urge to urinate, but producing nothing

urination; involuntary, incontinence; morning

late morning

Kidneys

pain, rigidness, region of kidneys

pain; region of

pain; aching; region of kidneys

pain; shooting (see sudden, sharp); sore, bruised

pain; shooting (see sudden, sharp); region of kidneys

Stomach

emptiness, weak feeling, faintness, hungry feeling; afternoon; 3 p.m.

burping, belching; bitter

burping, belching; empty; night

7 p.m.

burping, belching; hot

heaviness, weight, oppression (see fullness); after eating

sensation of movement in stomach; trembling

pain; after rising

pain; cramping, griping, constricting; morning; in bed

pain; cramping, griping, constricting; standing erect

pain; sudden, sharp; extending to other parts; upwards

sinking (see emptiness)

thirst; afternoon

thirst; evening

Eating

aversion to certain foods or drinks; coffee

aversion to certain foods or drinks; cold drinks (see water, cold)

aversion to certain foods or drinks; all drinks

aversion to certain foods or drinks; water

cold

Nausea

nausea; afternoon; 1 p.m.

nausea; afternoon; 2 p.m.

nausea; afternoon; 4 p.m.

nausea; during backache

nausea; on lying down

nausea; from noise; from music

nausea; from noise; from sound of organ

nausea; from pressure on painful spot; stomach

Vomiting

vomiting; strong and sharp (acrid)

vomiting; water

▲   RECTUM, ANUS, STOOL

Rectum

Haemorrhoids

night

bluish

external

hard

walking

Pain

burning; during stool

soreness

urge to stool, or urinate, but producing nothing; during diarrhoea

urge to stool, or urinate, but producing nothing; before stool

urge to stool, or urinate, but producing nothing; during stool

urge to stool, or urinate, but producing nothing; after stool

Swelling of anus

Urging, desire to stool (see pain

urge to stool, or urinate, but producing nothing); night

urge to stool, or urinate, but producing nothing); during stool

Stool

Food appears to be passed undigested (lientery)

Odour; offensive

Shooting out

Soft

Yellow

▲   GENITALS ETC

Urine

Odour; mouldy

Urethra

Urethra (urinary part of genitals); pain; while urinating; at close of urination

pain; soreness

Female

Female

vaginal discharge

vaginal discharge; bloody

vaginal discharge; milky

Genitals

Congestion of eyes

Rigid muscles.

Male; sexual passion; increased; excessive

Menses

Female; Irregular menstruation, with palpitation

▲   EXTREMITIES, LIMBS

Extremities, limbs

Pain in right popliteal space

Burning and tingling in spine

Hands and feet numb

Sudden jerking of limbs on going to sleep

Tetanic convulsions

Locomotor ataxia

Numbness in paralyzed parts, crampy pains in limbs.

Chilliness; upper limbs; right

Coldness

Constriction

upper arm

upper arm; above the elbow

Cramps

hand

knee; hollow of knee

calf; in bed

foot

Heat

upper limbs

hand

lower limbs

Heaviness

tired limbs

upper limbs

Movements and positions

jerking; falling asleep

difficulty raising; upper limbs

trembling; upper limbs

late morning; 11 a.m.

evening

evening; 7 p.m.

trembling; hand

trembling; lower limbs

trembling; leg; morning

Numbness (see tingling)

upper limbs

right

evening

7 p.m.

forearm; afternoon, 5 p.m.

hand

fingers; third finger

evening; 7 p.m.

leg

foot

Pain

joints

after walking

upper limbs

movement

shoulder

after dinner

elbow

forearm

evening; 8 p.m.

wrist

evening

opposite side to thumb

hand

back of hand

joints of hand

fingers; first finger; joints of

lower limbs

morning; 9 a.m.

hip

extending to other parts; groin

thigh

noon; after walking

knee

bending limb

paralytic

while sitting

on walking

after walking

lower leg

toes; first toe (large toe)

aching; forearm

aching; wrist

aching; hand; joints of

aching; fingers; first finger; joints

aching; lower limbs; thigh; extending downward

aching; lower limbs; knee

aching; ankles; while sitting

aching; toes; first toe (large toe)

burning; hand; palm

pulling; shoulder

rheumatic

pulling; leg; tendons

gnawing, biting; leg

shooting (see stitching, sudden, sharp); shoulder

morning

sore, bruised; joints

stitching, sudden, sharp; joints

stitching, sudden, sharp; upper limbs

evening; 5 p.m.

stitching, sudden, sharp; shoulder

morning

stitching, sudden, sharp; elbow

stitching, sudden, sharp; knee

Perspiration; hand

Pulsation, throbbing

upper limbs

upper limbs; burning

hand

burning

Restlessness

upper limbs

Skin

discoloration; upper limbs; small, purple spot

itching; upper limbs

itching; hand; palm

Stiffness

joints; evening, 9 p.m.

lower limbs

hip

knee

Thrilling sensation (see shuddering); leg

Tingling, prickling, asleep (see numbness); forearm

forearm; extending to fingers

Unsteadiness; knee

Weakness

wrist

hand

leg

evening

ankle

foot

▲   FEVER AND CHILL

Fever and chill

Shaking, shivering, rigors; from a draft of air

At certain time of day or night; from 8 p.m.

Dry heat

▲   GENERALITIES

Sleep and dreams

Deep

morning; after 5 a.m.

Disturbed

Dreams

amorous

animals, insects, beasts; animals

animals, insects, beasts; being a lion

being blind

frightful

vivid

Falling asleep; afternoon

Heavy

Restless

Sleepiness, tiredness

morning

while riding

late morning

9 a.m.

11-30 a.m.

noon

afternoon

3 p.m.

evening

after dinner

while riding

while travelling

after walking in open air

Sleeplessness, insomnia

night; from before midnight

Waking

2 a.m.

frequent

sudden

Yawning

daytime

Convulsions

Convulsions

rapid muscle spasm

in women; during period

with tetanus rigidity

Perspiration

Morning; after waking

Generalities

Collapse

after vomiting

Faintness, fainting

morning

during stool

on moving

Jerking; on going to sleep

Numbness; externally

Pain

appear suddenly

pressing; internally

Pulsation

night

midnight

externally; while sitting

internally

Pulse

frequent, accelerated, elevated, exalted, fast, innumerable, rapid

frequent, accelerated, elevated, exalted, fast, innumerable, rapid; morning

frequent, accelerated, elevated, exalted, fast, innumerable, rapid; and intermittent

irregular

heavy; and slow

slow

small

soft

strong

weak

wiry

Symptoms not symmetrical; left

Tension; muscles

Twitching

twitching, involuntary movements (chorea); right side

twitching, involuntary movements (chorea); one sided

on going to sleep

Weakness (see lethargic, weariness)

daytime

morning

8 a.m.

morning; 9 a.m.

late morning

10 a.m.

afternoon

1 p.m.

4 p.m.

evening; 7 p.m.

evening; 8 p.m.

evening; 9 p.m.

night; 9 p.m.

night; 10 p.m.

from ascending stairs

lying

after stool

walking

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